Isabella C. Felli is a Professor of Chemistry at the University of Florence (Università degli Studi di Firenze, Italy) and a leading researcher at CERM/CIRMMP, a European reference infrastructure for magnetic resonance. She is internationally recognised for her pioneering contributions to biomolecular NMR spectroscopy, particularly in the study of intrinsically disordered proteins (IDPs) and other complex or highly flexible systems that challenge traditional structural biology approaches. Her work focuses on developing innovative heteronuclear NMR methodologies, including advanced 13C-detection strategies that enhance sensitivity and resolution for proteins with low proton density or dynamic regions. These tools have provided new insights into conformational ensembles, disorder-to-order transitions, and transient interactions relevant to cell signaling and neurodegeneration. Prof. Felli has authored numerous high-impact publications, led international collaborations, and contributed to major European projects in magnetic resonance. Her research continues to expand the capabilities of NMR for characterising challenging biomolecules with high biological and therapeutic relevance.